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Enzymes are large proteins that speed up the rate of a chemical reaction by acting as a catalyst 🙈 A catalyst provides the necessary environment for the reaction to occur, thereby quickening it 🙌 Certain catalysts work for certain kinds of reactions; in other words, each enzyme has a particular type of reaction that it can activate. Enzymes can be very fussy and sometimes need to be in certain environments or conditions to work well—or at all. A few enzymes are even susceptible to damage, like when they’re exposed too hot. The enzyme might not work properly to initiate a chemical reaction if it is damaged.
The cell can produce reactive species during normal cellular metabolism. This chemical reaction with biomolecules like nucleic acid, protein, and lipids may cause their oxidative modification, which could lead to changes in their compositions or potential damage to their activities. The cells are equipped with many antioxidant defense mechanisms such as vitamins and metabolites that can neutralize the damaging effects of reactive substances and/or byproducts. Any perturbation in the balance in the level of antioxidants and the reactive species results in a physiological condition called “oxidative stress.” A catalase is one of the crucial antioxidant enzymes that mitigates oxidative stress to a considerable extent by destroying cellular hydrogen peroxide Catalase is required to make water and oxygen. Deficiency or malfunction of catalase is postulated to be related to the pathogenesis of many age-associated degenerative diseases like diabetes mellitus, hypertension, anemia, vitiligo, Alzheimer’s disease, Parkinson’s disease, bipolar disorder, cancer, and schizophrenia. Many laboratories are currently investigating the possibility of using it as a drug to treat such conditions. The paper covers the indirect and direct involvement of deficiencies and/or a deficiency. modification of catalase in the pathogenesis of some important diseases such as diabetes mellitus, Alzheimer’s disease, Parkinson’s disease, vitiligo, and acatalasemia. The efforts to explore the possibility of treating these conditions using catalase, a protein therapeutic drug, have been also described. Ashley James, Hegang (China) on March 26, 2021.
Introduction Have you ever thought about how everything works? food that you eat gets digested? It is not only the acid in your stomach that breaks down your food—many little molecules in your body, called enzymes, help with that too. The special proteins called enzymes speed up chemical reactions like the digestion of food. There are actually thousands of enzymes that your body has which work round-the-clock. keep you healthy Active. This is the best way to learn. science activity you will investigate You can learn more about catalase (an enzyme that helps protect the body from harm) by looking at this link. Kayla M. from Ganzhou, China December 12, 2020.
Shemika Arce, at pdb101.rcsb.orgLiving with oxygen can be dangerous. Oxygen is essential for our survival. However, oxygen can be dangerous because it’s a reactive chemical that could cause severe problems. Oxygen can easily be converted to other reactive compounds, which is one of its dangers. The electrons in our cells are continuously shuttled around by carriers molecules like riboflavin, niacin, and other riboflavin-derived carrier molecules. An electron can accidentally transfer to another carrier molecular if it comes into contact with oxygen. The oxygen is converted into potentially dangerous compounds like superoxide radicals or hydrogen peroxide. These can cause damage to the fragile sulfur atoms as well as metal ions within proteins. Free iron ions can also convert hydrogen peroxide to hydroxyl radicals in cells. These dangerous molecules can damage and alter DNA. Another theory is that this type oxidative damage builds up over time, leading to age.